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P&T News

November 25

First fixed-combination clindamycin/benzoyl peroxide medication for once-daily treatment
Drug captures almost half of second-line share among newly diagnosed patients
Dry-delivery technique eliminates need for needles, liquid storage
Agency recommends adding important safety information to product labels

November 24

Monoclonal antibody increases number of deaths in phase III trial
Patterns of genetic activity could help in early detection
‘Team-based care’ might be the solution

November 21

Surgical membrane heals damage with vitamin A derivative
No approved vaccines are available for this indication
‘The crisis is worsening,’ editorial writers say
Tablet is difficult to crush, break, or dissolve for illicit use
GAPVAC trial matches vaccines to individual glioblastoma patients

November 20

Price of Sovaldi caught payers by surprise, expert says
Seventy percent response rate observed in ongoing phase II study
Oncologists expected to embrace lower-cost alternatives to Neupogen

November 19

FDA submission expected later this year

November 18

Equipment could be ‘game-changer’ in glioblastoma treatment
Researchers investigate famciclovir/celecoxib combo
NIH studies find limited kidney benefit from more rigorous blood pressure treatment

November 17

More than 80% of patients show no progression of joint structural damage
Approval based on data from two pivotal studies
Second virus-related death in U.S.
Treatment improves progression-free survival compared with chemotherapy alone
Presence of type-1 interferon helps guide treatment choices

November 14

New testing sought for Mallinckrodt and Kudco Ireland ADHD drugs
Two-day meeting of experts seeks to prioritize global efforts
Improper contact lens habits pose major risk for serious infections
Approval decision expected early next year with ‘priority review’
Results are obtained within 90 minutes

November 13

No FDA-approved meds can counteract antiplatelet effect
Analysis combines questionnaire, genetic profiling, and mammography scans
Experts clarify areas of agreement across multiple guidelines
TNF-alpha inhibitors face competition from biosimilars

November 12

Procalcitonin levels differentiate bacterial and viral infections
Health workers can grab quick refresher course
Treatment meets all primary and secondary endpoints
Health care executives see $1 million in added supply-chain costs



From Sovaldi to Ebola: A Wide-ranging Interview with Dr. David Nash

A leading authority on population health, Dr. David Nash is optimistic about the future of disruptive innovation to improve healthcare in the U.S. The interview was conducted by P&T Editor Sonja Sherritze.


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